After reading some of the articles and forums out there, I see that she is likely suffering from some kind of cognitive deficiency resulting from the loss/depletion of her senses and the early signs of kidney failure. As much as it pains me to say this, I realize that she may be suffering a great deal. I hate that she has to be drugged up on valium to have a decent quality of life. It breaks my heart. She is the sweetest dog I have ever had/encountered and I hate to see her going through this. We may be facing a tough decision in the next few days.
Since dogs can have allergies to certain medications, plants, foods, etc., it is again advisable to work with your veterinarian or a homeopathic specialist for pets to find a healthy solution for your anxious dog. Simply let your vet know you’d rather avoid prescription anti-anxiety drugs or medication or try all organic solutions first and he or she will guide you to options for your pet.  With pets, what works for one dog’s behavior modification may not work for another. Even if you’ve received advice from other pet owners or discussion forums, confirm with your doctor before trying anything new.
Unless you plan to keep your dog outdoors--and few of us do because it's not recommended--you'll need to teach your dog where to eliminate. Therefore, house training (also called housebreaking or potty training) is one of the first things you need to work on with your dog. Crate training can be a very helpful part of the training process. This includes house training as well as many other areas of training:
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