After reading some of the articles and forums out there, I see that she is likely suffering from some kind of cognitive deficiency resulting from the loss/depletion of her senses and the early signs of kidney failure. As much as it pains me to say this, I realize that she may be suffering a great deal. I hate that she has to be drugged up on valium to have a decent quality of life. It breaks my heart. She is the sweetest dog I have ever had/encountered and I hate to see her going through this. We may be facing a tough decision in the next few days.
In most cases, dogs will naturally bark when someone they don't know is approaching. You can put this to good use by teaching him when to bark and when to stop. Each time your dog barks at a stranger, let him bark 2 or 3 times and then tug on his leash and give the command "Quiet". When he does, be sure to give him a treat and praise him. This lets him know no when he should bark and when he shouldn't.

In the 1980s veterinarian and animal behaviourist Ian Dunbar discovered that despite evidence on the peak learning periods in animals, few dog trainers worked with puppies before they were six months old.[25] Dunbar founded Sirius Dog Training, the first off-leash training program specifically for puppies, which emphasizes the importance of teaching bite inhibition, sociality, and other basic household manners, to dogs under six months of age.[31] Dunbar has written numerous books, and is known for his international seminar presentations and award-winning videos on puppy and dog behavior and training.[32]

Certain breeds, such as Doberman Pinschers, German Shepherds, Border Collies, Labrador Retrievers and Golden Retrievers, have reputations as being easier to train than others, such as some hounds and sled dogs. Dogs that have been bred to perform one task to the exclusion of all others (such as the Bloodhound or Husky), or that have been bred to work independently from their handler (such as terriers), may be particularly challenging with obedience training.

In the car, these solutions may also help with mild motion sickness your dog might suffer from. On road trips, take plenty of breaks so your pet can have room to roam and urinate. This should all be factored into your travel time so there’s plenty of time for stopping along the way. Being cooped up for too long is one way to surely make your dog feel restless and anxious.

I would like to restate that she never has this behavior at home and it feels like it only happens when she is in a new place. I recently took her on a longer walk, to a place she had never been ( we didn’t have to use the car) and my Fiance went into the store while I waited with her outside. The extreme panting began again, and I attempted to soothe her and kept a tight grip on the leash. Then an unknown man came out of the store, and our lab charged him, and wailed me into a pole so hard that it caused tissue damage on my arm. I must admit I am not the strongest person I know, but her pull was simply uncontrollable.
My Shiba Inu is 22 months old and he has always been a good traveler. 3 months ago he became extremely anxious whem traveling in the car with me. He makes the yowling Shiba noises and paces and tries to chew my seatbelt from the back seat. He is calmer when we ride with a friend and I can be a passenger with him. The only thing that occurred in our travels last October that could have triggered this is 3 different 40 mile trips in the rain. He became increasingly anxious during each trip. Portions of the road were slanted so the rain beat up underneath the car. I’ve tried sitting in a parked car with him while giving him treats if he can remain calm whilevthe carvis stationary. It helped temporarily. Do you have any better tips on desensitizing? They are such a bright breed. Driving now seems to pose a threat to him.
^{To help my dog with his anxiety, I first try to identify the source of his anxiety. That is difficult to do without looking at the dog, his environment, routine, and other surrounding context. If I am not sure where the anxious behavior is coming from, I may visit with several good professional trainers. They can observe my dog, give me their opinion as to what is causing the anxiety, and why. Sometimes, I am too close to the problem, so it helps to get professional opinions from others.}
4. Consider changing your vet if he/she isn’t tuned in to your dog’s needs. While some vets are great with nervous and aggressive dogs, others are still very old school; they don’t listen to owners and use invasive and rough handling. There are, however, new techniques out there for vets dealing with anxious dogs. Dr. Sophia Yin has developed a program for vets that focuses on low-stress handling, which can make a huge difference in your dog’s anxiety levels. And Dogs in Need of Space has a list of vets who go the extra mile for anxious dogs; if you do want to change your vet, it’s a good place to start.
The use of medications can be very helpful, especially for severe cases of separation anxiety. Some dogs are so distraught by any separation from their pet parents that treatment can’t be implemented without the help of medication. Anti-anxiety medication can help a dog tolerate some level of isolation without experiencing anxiety. It can also make treatment progress more quickly.
Clicker training, a common form of positive reinforcement, is a simple and effective dog training method. Although it is still fine to train your dog without clicker training, many people find it helpful. With clicker training, you can easily and effectively teach your dog all kinds of basic and advanced commands and tricks. It's fast and easy to learn how to clicker train your dog